Vanizem®
Unlock Your Natural Calm

The Bliss Molecule: Anadamide's Role in Well-Being

Vanizem is nature’s way of helping your body hold on to happiness. At the heart of its power is the “bliss molecule” anandamide—your body’s own feel-good neurotransmitter that elicits calm, balance, and joy.

Discovered in the early 1990s, anandamide has become a focus of intense research in neuroscience and psychology because of its role in regulating mood, cognition, and even pain.

Anandamide is a neurotransmitter and endocannabinoid, a type of molecule that the human body naturally produces to help regulate a variety of physiological processes. Its name comes from the Sanskrit word “ananda,” meaning bliss or joy, reflecting its mood-enhancing effects.

Research demonstrates that Vanizem helps preserve anandamide by inhibiting its breakdown enzyme, fatty acid amide hydrolase (FAAH).

Breaking the Stress-Mood-Sleep Cycle

The Stress-Mood-Sleep cycle is a self-reinforcing loop where stress, mood problems, and sleep disturbances reinforce and amplify each other in a negative way.

Stress is the Trigger

When you encounter stress, whether it is work deadlines, financial pressure, or emotional strain—your body activates the hypothalamic-pituitary-adrenal (HPA) axis. This leads to higher cortisol and adrenaline levels. While useful in short bursts, chronic stress dysregulates these hormones, making it hard for the nervous system to “switch off.”

Mood Makes it Worse

Elevated cortisol alters brain chemistry, reducing the availability of serotonin, dopamine, and anandamide (the “bliss molecule”). This can create a state of low mood, irritability, or even anxiety. Negative mood reinforces the perception of stress, amplifying the body’s stress response.

Sleep Denied Prevents Equilibrium

Stress hormones directly interfere with the circadian rhythm. High cortisol in the evening delays melatonin release, making it harder to fall asleep. When sleep is shortened or fragmented, restorative and REM cycles are disrupted. Poor sleep then makes the brain more reactive to stress the next day, lowering emotional resilience.

Vanizem Can Help

By reducing stress and supporting mood, Vanizem can help can “reset” this cycle.* Even small improvements in one area can ripple across the entire system.

Vanizem protects and enhances levels of anandamide (the “bliss molecule”) by inhibiting FAAH (the enzyme that breaks it down). More anandamide means greater activation of CB1 (cannabinoid receptor type 1) receptors in the brain. CB1 activation reduces excessive release of stress neurotransmitters, which calms the stress response and lowers cortisol output. By supporting anandamide and endocannabinoid tone— your body’s baseline level of calm and balance–Vanizem helps improve resilience, calm, and positivity.*

When stress is turned down and mood is under control, nighttime cortisol naturally declines, and melatonin rhythms are less disrupted. Sleep comes more easily and is more restorative. The next day becomes less stressful.*