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    Seth Flowerman
    President and CEO

Zynamite® PX

More Power. One Hour. With Enhanced Recovery.
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OVERVIEW

Improved peak power. Reduced lactate build-up. Enhanced recovery.

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4 Clinical Trials

Zynamite PX is backed by science that supports unique benefits.

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Low Dose

Zynamite PX helps people who exercise, rapidly with a single small dose

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3.8%

Zynamite PX improves Peak Power after just one dose – in one hour!

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7 Industry Awards

Zynamite has won 7 international best-in-class ingredient awards since it was introduced in 2018.

FEATURES & BENEFITS

 

Multiple clinical trials

Experiential & fast-acting

Enhanced peak power

Reduced blood lactate levels

Accelerated recovery

Improved Physical Performance

Safe, side-effect free

Vegan suitable

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CERTIFICATIONS

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GLUTEN-FREE

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SOLVENT-FREE

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BSCG CERTIFIED

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NON-GMO

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HALAL

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KOSHER

Experiential Sports Performance Enhancement

Zynamite PX is a patented, synergistic combination of a Mangifera indica extract and Sophora japonica extract (standardized to 50% quercetin) that offers a unique set of benefits in active/sports nutrition products that consumers will experience.

Mangifera indica

Mangifera indica is mango! It has been an important part of the Ayurvedic medical tradition for 4,000 years.

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Sophora japonica

Sophora japonica is also known as the Japanese pagoda tree. It is one of the fundamental herbs used in traditional Chinese medicine.

Rhodiola rosea

Rhodiola rosea is a plant native to remote Arctic climates in Asia, Europe and North America.

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Exciting Phytochemistry

The root of the plant contains around 140 chemical compounds including phenols, rosavin, rosarin, salidroside and more.

Detail 1

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

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Detail 2

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

RESEARCH

Zynamite PX offers unique benefits to active/sports formulations you may not find with other ingredients. The science is on both men and women – and the fast-acting boost to peak power in just one hour offers you the ability to ‘move the needle’ with your product.

Research that builds trust with consumers.

In 2018, a double-blind cross-over clinical study was conducted to determine whether a single dose of 420 mg of Zynamite PX administered one hour before exercise would increase repeated-sprint performance. Subjects performed three Wingate tests interspaced by 4 minutes and a final 15-second sprint after ischemia. Peak power was improved by 3.8% versus placebo in subjects using Zynamite PX. One interesting result was that the quercetin dose was about 25-50% lower than that associated with quercetin ergogenic effects in previous studies, suggesting that this combination may have synergistic effects.


Zynamite PX Improves Peak Power

Peak power is an important measure of physical performance.

Power is the rate of adenosine triphosphate (ATP) used over a single or multiple maximal effort against a submaximal load. Peak power is the greatest output or production of work over a given amount of time. Power accounts for a combination of strength, velocity, force and neuromuscular adaptations.

Power tests help create an athletic profile and can also be used as indices of fitness or performance adaptation over time. Power is especially important since tests that focus on raw strength or speed do not account for the neuromuscular and energy transfer properties captured by power tests. Power tests are important for sports that require explosive energy such as sprinting, weightlifting, football, soccer, basketball, tennis and other sports.

Support for exercise recovery

In a second clinical study on Zynamite PX, 48 subjects ran a 5K race to randomly assign them to two treatment groups, matched by sex and 5K performance. Two weeks later, they participated in a 10K race followed by 100 drop jumps (59 cm height) to elicit exercise-induced muscle damage (EIMD).

Results of the study suggest that a single 420 mg dose of Zynamite PX taken one hour before competition, followed by three additional doses every eight hours, attenuated the pain elicited by competitive exercise and accelerated the recovery of muscle performance.

 

Zynamite PX Accelerates Recovery

Zynamite Improves Elite Athletic Performance at One Hour

Thirty-eight male basketball players from the top three national teams in Greece received either a  placebo or Zynamite PX one hour prior to participating in a basketball exercise stimulation test (BEST). Thirty-eight male basketball players from the top three national teams in Greece received either a  placebo or Zynamite PX one hour prior to participating in a basketball exercise stimulation test (BEST). Participants in the supplement group were faster, showing a statistically significant improvement in mean circuit lap time compared to those in the placebo group. The Zynamite PX group also showed a significant reduction in their subjective rating of perceived exertion, which is used to assess muscular effort and fatigue... 


Participants in the supplement group were faster, showing a statistically significant improvement in mean circuit lap time compared to those in the placebo group. The Zynamite PX group also showed a significant reduction in their subjective rating of perceived exertion, which is used to assess muscular effort and fatigue. 

 

A Unique Set of Benefits

Clinical studies with Zynamite PX point to intriguing benefits and offer you the ability to create compelling messaging for your customers. It offers a low dose – compared to many ‘power’ ingredients that suggest doses ranging from 600 mg to 4 mg! Studies with Zynamite PX point to ‘same day’ benefits – whereas most ingredients were studied in situations where weeks of training were required to see the benefits.

 

CLINICAL HIGHLIGHTS

Clinical Study: Zynamite improves peak power in one hour

ZynamitePX Increased Peak Power Output chart and image

A double-blind cross-over clinical study was conducted to determine whether a single dose of 420 mg of Zynamite PX administered one hour before exercise would increase repeated-sprint performance. Subjects performed three Wingate tests interspaced by 4 minutes and a final 15-second sprint after ischemia. Peak power was improved by 3.8% versus placebo in subjects using Zynamite PX. 

 

GET THE RESULTS

ZynamitePX Increased Peak Power Output chart and image

Clinical Study: Zynamite supports exercise recovery

ZynamitePX Accelerated Recovery of Muscle Performance chart and image

48 subjects participated in a 10K race followed by 100 drop jumps (59 cm height) to elicit exercise-induced muscle damage (EIMD). Results of the study suggest that a single 420 mg dose of Zynamite PX taken one hour before competition, followed by three additional doses every eight hours, attenuated the pain elicited by competitive exercise and accelerated the recovery of muscle performance.

 

GET THE RESULTS

ZynamitePX Accelerated Recovery of Muscle Performance chart and image

Clinical Study: Zynamite PX Improves Exercise and Recovery Biomarkers

Zynamite PX sprinter Martinez-Canton M study

Twenty-five volunteers were assigned to a control group or supplementation group receiving 140 mg of Zynamite® + 140 mg quercetin/8 h for 2 days. They performed incremental exercise to exhaustion (IE) followed by occlusion of the circulation in one leg for 60 s. Afterwards, the cuff was released, and a 30 s sprint was performed, followed by 90 s circulatory occlusion (same leg).  The study showed that Zynamite PX elicits muscle signaling changes in resting skeletal muscle resembling those described for exercise training and partly abrogates the stress kinases responses to exercise as observed in trained muscles. Martinez-Canton M, et al. Nutrients 2023;15:2848.

 

GET THE RESULTS

Zynamite PX sprinter Martinez-Canton M study

Clinical Study: Zynamite PX Improves Physical Performance in Elite Athletes

Zynamite PX basketball player Bourdas DI et al. Nutrients 2023 chart

Significant decrease in mean circuit time vs. placebo
Thirty-eight male basketball players from the top three national teams in Greece received either a placebo or Zynamite PX one hour prior to participating in a basketball exercise stimulation test (BEST). Participants in the supplement group were faster, showing a statistically significant improvement in mean circuit lap time compared to those in the placebo group. The Zynamite PX group also showed a significant reduction in their subjective rating of perceived exertion, which is used to assess muscular effort and fatigue. Bourdas DI et al. Nutrients 2023;16:170.

 

GET THE RESULTS

Zynamite PX basketball player Bourdas DI et al. Nutrients 2023 chart
ACCESS CLINICAL STUDIES

MARKET OPPORTUNITIES

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Active/Sports Nutrition

Zynamite PX is ideal for pre-workout formulations and can also be effective in post-workout recovery-type products.

APPLICATIONS

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BEVERAGES

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CAPSULES

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CHEWS

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GUMMIES

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EFFERVESCENTS

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POWDERS

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RTDS/SHOTS

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STICK PACKS

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TABLETS

ORIGIN STORY & INSIGHTS

A Global Search for Performance

PLT partner Nektium Pharma began a global search for an ingredient that could support both human cognitive function and sports performance in 2015. This search involved reviews of the ethnobotanical literature and plants used in Ayurvedic and Traditional Chinese Medicine.

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Prominent Mangifera indica Leaves

The flavone mangiferin was found to be a prominent compound in a number of the original fifty candidate plants, including in the leaves of the domestic mango, Mangifera indica, and in plants belonging to the genera Hypericum, Salacia, Cyclopia, and Canscora.

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Standardized Mangifera indica

The research team at Nektium developed an extract of Mangifera indica leaves standardized to the content of mangiferin – produced at Nektium’s cGMP facilities. This extract was trademarked Zynamite.

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An Ancient Chinese Herbal Remedy

Sophora japonica, also known as the pagoda tree, is a species of deciduous tree in the pea family Quercetin is a flavonoid extracted from the flower of this tree.

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Research Uncovers New Possibilities

Nektium examined the potentials of Zynamite in combination with a broad range of botanicals. The combination with quercetin showed surprising sports performance benefits.

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QUALITY

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Certified Sports Grade for U.S. Market

In July 2020, PLT announced the availability of third-party BSCG Certified Drug Free® Zynamite PX. PLT manufacturing partner Nektium Pharma has established an on-going program with the Banned Substances Control Group (BSCG) to test and certify materials sold as Sports Grade. The testing program covers 496 drugs in total, including 272 drugs that are banned by a broad range of sports organizations. This sports certified grade is critical in sports nutrition products.

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"Spanish nutraceutical firm Nektium won Nutraingredient’s Nutrition Research Project award in 2019 for Project Zynamite.“


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RESOURCES

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Zynamite® PX Product Sheet
April 16, 2020
Behind every ingredient solution is an even better story, download the product sheet to learn more.
Industry NewsSales Collateral
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STACK3D: Study shows Zynamite PX improves performance and reduces fatigue within an hour 28686E9C-0345-47E1-B5C6-FB030592A87D
January 31, 2024

A study published in “Nutrients” this month centered around a double-blind, crossover trial involving 38 top-level basketball players. It evaluated the effects of a single dose of Zynamite PX taken one hour before participating in a basketball exercise stimulation test. The results showed that participants who took the Zynamite variant saw significant improvements in mean circuit lap time and a reduced rating of perceived exertion compared to placebo, indicating enhanced performance and reduced fatigue.

Industry NewsIndustry News
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Nutrition Insight: Zynamite PX shown to enhance speed and recovery in professional basketball players 28686E9C-0345-47E1-B5C6-FB030592A87D
1/30/2024

Nektium’s sports nutrition offering Zynamite PX — a composition of its signature mango leaf extract and quercetin — has demonstrated significant improvements to athletic performance in professional basketballers, according to a recent study. 

Industry NewsIndustry News
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Nutraceutical Business Review: Zynamite plus quercetin shown to boost athletic performance in high-level basketball players 28686E9C-0345-47E1-B5C6-FB030592A87D
1/29/2024

A supplement containing Zynamite and quercetin delivered significant improvements to athletic performance in an independent scientific study featuring national-level basketball players in Greece.

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Zynamite® PX Shown to Boost Performance in High Level Athletes Within One Hour
January 25, 2024

New Study Demonstrated that National-Level Basketball Players in Greece were Faster and had Significantly Reduced Perceived Exertion

Industry NewsPress Releases
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Effects of a Singular Dose of Mangiferin–Quercetin Supplementation on Basketball Performance: A Double-Blind Crossover Study of High-Level Male Players
January 1, 2024

Pre-exercise mangiferin–quercetin may enhance athletic performance. This study investigated the effect of mangiferin–quercetin supplementation on high-level male basketball players during a basketball exercise simulation test.

Industry NewsClinical Research
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A Mango Leaf Extract (Zynamite®) Combined with Quercetin Has Exercise-Mimetic Properties in Human Skeletal Muscle
June 23, 2023

Zynamite PX®, a mango leaf extract combined with quercetin, enhances exercise performance by unknown molecular mechanisms.

Industry NewsClinical Research
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New Zynamite® Study Adds to Growing Scientific Portfolio for Award-Winning Ingredient Platform
August 18, 2020
Seventh Clinical Trial Demonstrates Benefits Starting at 30 Minutes
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PLT Now Offers Third-Party Certified Sports Grade of Zynamite® PX in U.S. Market
June 3, 2020
New Third-Party Certification Awarded to Zynamite PX for Sports Grade
Industry NewsPress Releases
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PLT Launches Zynamite® PX for Sports Nutrition
March 3, 2020
New Formulation of Award-Winning Ingredient has been Clinically Shown to Improve Peak Power from a Single Dose at One Hour After Use
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