MegaNatural-BP®
Cardio Health Support

Subjects were given 300 mg/day of MegaNatural-BP or a placebo. At eight weeks, MegaNatural®-BP was found to help maintain blood pressure levels (systolic and diastolic) within the normal range.* Robinson M, Lu B, Kappagoda T. Effect of grape seed extract in subjects with pre-hypertension. 13th World Congress on Heart Disease, Vancouver, B.C., 2007, pp. 239-42.

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Subjects were given a.) placebo, b.) 150 mg MegaNatural®-BP per day and c.) 300 mg MegaNatural-BP per day for four weeks. At four weeks, both dosages of MegaNatural®-BP were found to help maintain blood pressure levels (both systolic and diastolic) within the normal range.* Sivaprakasapillai B, Edirisinghe I, Randolph J, Steinberg F, Kappagoda T. Robinson M, Lu B, Edirisinghe I, Kappagoda CT. Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome. Metabolism. 2009; 58:1743-1746.

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Subjects were given 300 mg/day of MegaNatural-BP or a placebo. At eight weeks, MegaNatural®-BP was found to help maintain blood pressure levels (systolic and diastolic) within the normal range.* Robinson M, Lu B, Edirisinghe I, Kappagoda CT. Effect of Grape Seed Extract on Blood Pressure in Subjects with Pre-Hypertension. J Pharmacy Nutr Sci. 2012;2:155–9.

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.70 subjects were given 300 mg/day of MegaNatural-BP or a placebo. At eight weeks, MegaNatural®-BP subjects had blood pressure values decrease by -3.0 mmHg for systolic BP and –1.4 mmHg for diastolic BP. Ras RT, Zock PL, Zebregs YE, Johnston NR, Webb DJ, Draijer R. Effect of polyphenol-rich grape seed extract on ambulatory blood pressure in subjects with pre- and stage I hypertension. Br J Nutr. 2013;110(12):2234-2241. 

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Middle-aged adults with pre-hypertension consumed a fruit-flavored beverage placebo or 150 mg MegaNatural®-BP twice per day (300 mg per day) in a fruit-flavored beverage for six weeks, preceded by two-week placebo run-in and four-week no-beverage follow-up. After six weeks, MegaNatural®-BP was found to help maintain blood pressure levels within the normal range. After four weeks of discontinuation of MegaNatural beverage, blood pressure increased to original levels. Park E, Edirisinghe I, Choy YY, Waterhouse A, Burton-Freeman B. Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomized, double-blinded, two-arm, parallel, placebo-controlled trial. Brit. J. Nutr. 2016; 115: 226-38.

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Obese and normal weight men were given either 300 mg/day of MegaNatural-BP or a placebo  Measurements were taken two hours post dose. MegaNatural-BP reduced systolic BP and arterial pressure  for both groups. The study suggests that acute supplementation with MegaNatural-BP reduced both SBP and MAP via a reduction in CO in obese individuals and decreased peripheral vasoconstriction in NBW group. Dillon KN, Shariffi B, Thompson B, Steele R, Kim JK. Effects of Acute Grape Seed Extract Supplementation on Hemodynamics in Normal Body Weight and Obese Males. J Nutr Sci Vitaminol (Tokyo). 2020;66(5):427-431.

Division I basketball players were given either 300 mg/day of MegaNatural-BP or a placebo  Progressive cycling exercise measurements were taken at 14 days. VO2 significantly decreased at 80% and 120% workloads after MegaNatural-BP supplementation compared to placebo (p = 0.041 and p = 0.031, respectively). The time to exhaustion trial had a significant increase after MegaNatural (p = 0.035). Nho H, Kim KA. Effects of Grape Seed Extract Supplementation on Endothelial Function and Endurance Performance in Basketball Players. Int J Environ Res Public Health. 2022;19(21):14223.