FLEXIR® Joint Health Complex

Joint & Bone Health for Global Markets

33%

Reduction in pain scores compared to placebo

32%

Reduction in stiffness compared to placebo

31%

Increase in overall functioning compared to placebo

14 Days

to enhanced joint comfort

	Clinically studied
	Novel formulation
	14 days to enhanced joint comfort
	Excellent regulatory profile
	Low 400mg/day dose
	Inhibits cartilage degrading enzymes (MMP3 & MMP-13)

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CERTIFICATIONS

VEGAN

GLUTEN-FREE

NON-GMO

HALAL

KOSHER

Boswellia serrata

Sourced from the forests of India, Boswellia has been used in Ayurvedic medicine for thousands of years.

Flexir circle

Curcumin

Curcumin is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family.

Haritaki

Haritaki is a species of Terminalia, native to South Asia from India and Nepal east to southwest China (Yunnan), and south to Sri Lanka, Malaysia, and Vietnam.

Rhodiola rosea

Rhodiola rosea is a plant native to remote Arctic climates in Asia, Europe and North America.

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Exciting Phytochemistry

The root of the plant contains around 140 chemical compounds including phenols, rosavin, rosarin, salidroside and more.

Detail 1

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

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Detail 2

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

A Novel, Synergistic Formulation of Three Botanicals

Today’s consumers are more conscious of joint and bone health than ever. They’re actively looking for new answers. This novel combination of ingredients delivers a new value proposition to your customers.

Studies of this new ingredient have suggested a mechanism of action for bone structure support through chondrocyte activation:

• Enhanced chondrocyte survivability under inflammatory (IL-1β) conditions (in vitro).
• Improved Glycosaminoglycan production by human chondrocytes.

All constituents of this new ingredient have been shown to be safe by multiple acute, sub-chronic, and chronic toxicity studies.

Clinical Efficacy

In a randomized, double-blind, placebo-controlled clinical trial, 105 men and women took 200 or 400 mg per day of Flexir or a matching placebo for 90 days. Those taking Flexir had statistically significant improvement in Total WOMAC scores compared to placebo.

Continuous improvement in Total WOMAC scores was observed throughout the 90-day trial. WOMAC subscores for pain, stiffness, and physical functioning were similarly improved in a dose-dependent manner throughout the duration of the trial. Visual Analog Scores (VAS) and Lequesne Functional Index (LFI) showed statistically significant improvement compared to placebo as well.

Clinical Study: Improvements in Joint Comfort at 14 Days

Flexir Reduction in Total WOMAC chart and image

In a double-blind, placebo-controlled clinical trial (105 men and women), daily consumption of 200 or 400 mg Flexir significantly improved joint pain scores in a dose-dependent fashion

GET THE RESULTS

ACCESS CLINICAL STUDIES

MARKET OPPORTUNITIES

Active/Sports Nutrition

Inflammation from exercise has similarities to the type of inflammation that occurs with the aging process. FLEXIR can help!

Bone, Joint & Muscle Health

FLEXIR provides support for healthy bone structure, reduction in joint pain and stiffness, and improved physical functioning.

HEALTHY AGING

Today’s seniors travel more, play more and do more than ever. FLEXIR can help them get moving and keep moving.

APPLICATIONS

CAPSULES

CHEWS

GUMMIES

EFFERVESCENTS

POWDERS

SOFT GELS

STICK PACKS

TABLETS

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ORIGIN STORY

A Novel Combination of Well-known Botanicals

FLEXIR is a novel, patent-pending ingredient based on Terminalia chebula, Curcuma longa (Turmeric) and Boswellia serrata (AKBA).

Tree Populations Safety and Health

PLT’s Boswellia serrata supply chain starts with collectors and aggregators who have worked with us for decades. These collectors are trained in sustainable gum tapping to maximize yield while maintaining the safety and health of the Boswellia serrata tree populations.

Long Established Partner

Over the last 25 years, PLT has worked with our innovation partner – Laila Nutraceuticals – to create an environment that can assure not only the highest quality Boswellia ingredient with proven efficacy, but an ingredient that the people who sell it and buy it can be proud of.

Value to Ayurvedic Medicine

Terminalia chebula is a deciduous tree native to South Asia from India and Nepal east to southwest China (Yunnan), and south to Sri Lanka, Malaysia, and Vietnam. It has seen long use in Ayurvedic medicine.

An Herbaceous Plant

Curcuma longa is also known as curcumin or turmeric. It is an herbaceous plant native to the Indian subcontinent and Southeast Asia and has been used for centuries in traditional and Ayurvedic medicine.

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PLT Mobility Solutions

At PLT, we are working on the concept of Mobility Solutions - making these solutions available for people of all ages and walks of life. We’re thinking about athletes who want to perform better and recover faster. We’re thinking about people who have physically demanding jobs who don’t want to or can’t take a day off from work. We’re thinking about anyone who has an active lifestyle who wants to embrace it despite the rigors. And yes, we’re thinking about the global aging population.

PLT Health Solutions’ leading portfolio of mobility support ingredients – based on more than a decade of ongoing research – has been developed to help you deliver innovative products that can capture the attention and the trust of consumers. All of our ingredients are backed by multiple clinical studies – and offer rapid improvements from a low dose - in just about any delivery system you can imagine.

Our international network, passionate team of experts and extensive industry knowledge is what sets us apart.

FLEXIR® Joint Health Complex

OVERVIEW

FLEXIR® is a novel combination of ingredients that delivers a new value proposition to your customers. It offers efficacy starting at two weeks – with a dose that is substantially lower than chondroitin and glucosamine.

33%

32%

31%

14 Days

FEATURES & BENEFITS

Clinically studied

Novel formulation

14 days to enhanced joint comfort

Excellent regulatory profile

Low 400mg/day dose

Inhibits cartilage degrading enzymes (MMP3 & MMP-13)