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    Seth Flowerman
    President and CEO

SEREZIN™ Restorative Sleep + Pain Relief

Deliver the Most Critical Aspect of Better Sleep - Better Mornings!
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OVERVIEW

Serezin™ Restorative Sleep + Pain Relief has been clinically shown to improve sleep across a wide range of measures and help people to wake feeling their best. Serezin supports getting to sleep faster and easier, improves sleep quality, with less nighttime and daytime pain and waking more alert in and a better mood.

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Within 1 Week

improved restorative sleep

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64% Better

restorative sleep

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93% Better

quality sleep

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2X Easier

morning waking

FEATURES & BENEFITS

 

Better sleep quality at 14 days

64% better restorative sleep* 

2.6x greater reduction in nighttime aches & pains*

75% greater reduction in daytime aches & pains

85% easier to fall asleep*

93% better quality of sleep*

2x easier morning waking*

93% better morning alertness*

2.2x improvement in overall mood*

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CERTIFICATIONS

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CLINICAL SCIENCE

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PATENTED

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KOSHER

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HALAL

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NON-GMO

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GLUTEN-FREE

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3RD PARTY VERIFIED SUSTAINABLE

Botanical support for better restorative sleep

Serezin™ Restorative Sleep + Pain Relief a synergistic blend of extracts from two well-known botanicals from the Ayurvedic medicine tradition - Boswellia serrata and Zingiber officinale (Ginger).The development of this complex involved screening hundreds of botanicals for their ability to improve sleep across a wide range of measures and help people to wake feeling their best.

BOSWELLIA SERRATA EXTRACT

Boswellia serrata extract is a gum resin isolated from what is known internationally as the frankincense tree. It has been used in traditional Ayurvedic medicine in India for centuries. Boswellic acid is the active ingredient in Boswellia serrata

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ZINGIBER OFFICINALE (GINGER)

Zingiber officinale is a flowering plant whose rhizome, ginger root or ginger, is widely used as a spice and a folk medicine. Ginger is in the family Zingiberaceae, which also includes turmeric (Curcuma longa), cardamom (Elettaria cardamomum), and galangal.

Rhodiola rosea

Rhodiola rosea is a plant native to remote Arctic climates in Asia, Europe and North America.

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Exciting Phytochemistry

The root of the plant contains around 140 chemical compounds including phenols, rosavin, rosarin, salidroside and more.

Detail 1

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

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Detail 2

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

 

RESEARCH


New Clinical Study Points to Broad Ranging Benefits

A 4-week double-blind, placebo-controlled study was conducted on 60 healthy men and women ages 50-70 years. Subjects self-reported disturbed sleep due to everyday aches and pains. They received either a 300 mg dose of Serezin a day or a placebo. Measurements were conducted at 1, 2 and 4 weeks.

 

Improved Restorative Sleep at Day 7

Subjects taking Serezin woke up feeling more rested and restored within the first week. By four weeks, subjects taking Serezin experienced a 64% greater improvement in restorative sleep than those taking placebo.

Reduced Every Day Aches and Pains in 1 Week

Significant improvements in pain scores started on Day 7 for the Serezin group. By Day 28, subjects taking Serezin experienced a 2.6x greater reduction in nighttime discomfort and a 75% greater reduction in daytime discomfort compared to the placebo.

Easier to Fall Asleep and Better Sleep Quality by Day 14

With statistically significant improvements by Day 14, subjects taking Serezin experienced improvements in getting to sleep that were 85% greater than those taking a placebo and 93% greater improvements in sleep quality than those taking a placebo as assessed by the Leeds Sleep Evaluation Questionnaire.

Improvements in Wake-Up Experience by Day 14

Subjects taking Serezin reported having a significantly easier time waking up in the morning and feeling more alert with better motor control upon waking, as assessed by the Leeds Sleep Evaluation Questionnaire.

Improved Mood Starting at Day 14

Mood states were evaluated using a validated questionnaire covering six domains: tension, depression, anger, vigor, fatigue, and confusion. Serezin subjects reported improved overall mood starting Day 14. For the study, subjects reported a 2.2x improvement in overall mood.

CLINICAL HIGHLIGHTS

Clinical Study: Improved Quality of Sleep and Better Waking

Serezin Restorative Sleep Questionnaire RSQ chart and image

A 4-week double-blind, placebo-controlled study was conducted on 60 healthy men and women ages 50-70 years showed that Serezin supports getting to sleep faster and easier, improved sleep quality, and delivers less groggy mornings with better alertness and mood.

 

GET THE RESULTS

Serezin Restorative Sleep Questionnaire RSQ chart and image

MARKET OPPORTUNITIES

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Restorative Sleep

Sleeping better at night is associated with a range of positive health outcomes, including improved quality of life. Studies suggest that more than 65% of consumers do not get enough restorative sleep.

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BONE, JOINT & MUSCLE HEALTH

Serezin has been clinically demonstrated to reduce everyday aches and pains – enhancing quality of sleep and improving mood and alertness all day.

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HEALTHY AGING

Having difficulty sleeping is something we all experience as we get older. Serezin™ Restorative Sleep + Pain Relief has been clinically shown to improve sleep across a wide range of measures.

APPLICATIONS

app-capsules

CAPSULES

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EFFERVESCENTS

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POWDERS

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STICK PACKS

app-tablets

TABLETS

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BEVERAGES

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CHEWS

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GUMMIES

ORIGIN STORY & INSIGHTS

An intensive search for a novel sleep solution

The development of Serezin started a desire to understand the potential for traditional Ayurvedic medicine to reduce the nighttime aches and pains that prevent people from getting their best sleep, in a safe, side effect-free way.

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Mutli-Component Screening

A program of research screened many botanicals for optimal performance in reducing nighttime aches and pains. This work led to pre-clinical studies to understand the mechanisms of action through which Serezin could contribute to reduced nighttime pain and improved sleep.

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Finding Synergy with Two Botanicals

The research uncovered a synergistic complex of two botanicals. Boswellia serrata extract has been used in traditional Ayurvedic medicine in India for centuries. Zingiber officinale is a flowering plant whose rhizome, ginger root or ginger, is widely used as a spice and a folk medicine.

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A Gold Standard Clinical Trial

With this preclinical evidence in hand, a human clinical trial was developed that examined performance across a wide range of sleep and waking measures, Serezin is a unique ingredient in the sleep market with a broad range of messaging opportunities for consumer products.

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“By providing relief for nighttime aches and pain, Serezin unlocks the benefits of restorative sleep to help folks have better days, every day.”

Jennifer Murphy, Director of Innovation & Clinical Development for PLT

RESOURCES

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Serezin™ Product Sheet
August 28, 2024

Behind every ingredient solution is an even better story, download the product sheet to learn more.

Industry NewsSales Collateral
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PLT Health Solutions Launches New Ingredient to Improve Restorative Sleep, Provide Pain Relief, and Enhance Daytime Mood and Vitality Within 1 Week
February 26, 2024

PLT Health Solutions, Inc. announced it is launching a groundbreaking new ingredient designed to promote restorative sleep by reducing daytime & nighttime pain.

Industry NewsPress Releases
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Nutraceutical Business Review: "PLT Health Solutions' Serezin improves restorative sleep, provide pain relief and enhance daytime mood" 28686E9C-0345-47E1-B5C6-FB030592A87D
2/26/2024

PLT Health Solutions, Inc. announced it is launching a novel ingredient designed to promote restorative sleep by reducing daytime & nighttime pain. 

Industry NewsIndustry News
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Nutritional Outlook: PLT Health Solutions launches new ingredient marketed for pain relief and sleep support 28686E9C-0345-47E1-B5C6-FB030592A87D
2/26/2024

PLT Health Solutions has announced the launch of a sleep support ingredient called Serezin Restorative Sleep + Pain Relief.

Industry NewsIndustry News
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Nutra Ingredients USA: PLT Targets Restorative Sleep with Botanical Blend of Aches and Pains 28686E9C-0345-47E1-B5C6-FB030592A87D
2/26/2024

Ingredient supplier PLT Health Solutions has entered the sleep category with its new Serezin-branded botanical formula.

Industry NewsIndustry News
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Nutraceutical Business Review: "PLT to focus on new ingredients and new science at Vitafoods Europe 2024" 28686E9C-0345-47E1-B5C6-FB030592A87D
4/26/2024

New Serezin Restorative Sleep + Pain Relief is clinically demonstrated to provide fast-acting nighttime and daytime pain relief, make falling asleep easier and promote waking up feeling more alert and refreshed

Industry NewsIndustry News
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