Spectramune® Immune Defense Complex

Clinically demonstrated to enhance innate, cell-mediated and humoral immunity

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23% Fewer ARIs

Spectramune subjects experienced 23% fewer days sick than those taking a placebo.

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30% Less Severe

Spectramune subjects taking either 250 mg or 500 mg experienced 30% less severe symptoms.

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23% Better QoL

Spectramune subjects had 23% better Quality of Life scores.

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2x Improvement

Spectramune subjects had a 2x improvement in psychological wellbeing in 3 weeks.

	Supports Innate and Adaptive responses
	Demonstrated impact on Adaptive immunity via cell-mediated and humoral immune responses
	Get sick less often: 23% fewer sick days*
	Recover faster and feel better: 30% less severe symptoms*
	Stay active and energized: 23% better quality of life scores*
	Feel stronger, mentally and physically: 2x improvement in psychological wellbeing in 3 weeks*
	More energy, more resilience: 2x improvement in vitality in 12 weeks*
	Strengthening immune surveillance: Increased White Blood Cells *

CERTIFICATIONS

VEGAN

GLUTEN-FREE

NON-GMO

HALAL

KOSHER

A novel botanical complex designed for full-spectrum immune support

Spectramune is a patented, synergistic combination of ashwagandha (Withania somnifera) and Haritaki (Terminalia chebula). This combination was selected from a screening process that examined 40 different botanicals known to have immune support properties.

Ashwagandha

Ashwagandha is an evergreen shrub in the nightshade family that grows in India, the Middle East, and parts of Africa. The plant, particularly its root powder, has been used for centuries in traditional Indian medicine.

Spectramune ingredient circle

Haritaki

Haritaki is a species of Terminalia, native to South Asia from India and Nepal east to southwest China (Yunnan), and south to Sri Lanka, Malaysia, and Vietnam.

Rhodiola rosea

Rhodiola rosea is a plant native to remote Arctic climates in Asia, Europe and North America.

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Exciting Phytochemistry

The root of the plant contains around 140 chemical compounds including phenols, rosavin, rosarin, salidroside and more.

Detail 1

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

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Detail 2

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

Clinical Studies Demonstrate Powerful Immune Support

Spectramune has been the subject of three human clinical studies. In a 12-week randomized, double-blind, placebo-controlled, parallel design study, 120 healthy men and women (age 30-60) were given 250 mg or 500 mg of Spectramune or a matching placebo. The primary outcome measured was upper respiratory symptom severity via the Wisconsin Upper Respiratory Symptoms Scale (WURSS-24). Testing of subjects was done at baseline, 3, 6, and 12 weeks. A range of biomarkers was measured at baseline and 12 weeks.

Reduced Incidence of Acute Respiratory Illness (ARI)
Subjects taking 500 mg of Spectramune experienced 23% fewer episodes of respiratory illness and 23% fewer days sick than those taking a placebo.

Improved Global, Symptom and Quality of Life Scores During Illness
During episodes of acute respiratory illness, subjects taking either 250 mg or 500 mg of Spectramune experienced 30% less severe symptoms, and those symptoms had a 23% reduction in impact on their daily activities compared to those taking placebo.

Enhanced Markers of Innate Immunity

Subjects taking Spectramune had an increased White Blood Cell (WBC) count, reflecting enhanced immune readiness and surveillance. They also had enhancement of NK cells, immune frontline defenders that improve the body’s ability to respond to threats.

Clinical Study: Spectramune Provides Broad Spectrum
Immune Support

In a four-week trial, healthy male and female subjects (35-60 years of age/) who self-identified with low perceived immune status consumed 500 mg/d of Spectramune versus a placebo. showed significant improvements across a broad range of immune cells – targeting innate, cell-mediated and humoral immunity.

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Clinical Study: Reduced Incidence of Acute Respiratory Illness (ARI)

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Subjects taking 500 mg of Spectramune experienced 23% fewer episodes of respiratory illness and 23% fewer days sick than those taking a placebo. .

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Clinical Study: Improved Psychological Wellbeing

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Subjects taking Spectramune experienced significantly improved psychological wellbeing within the first three weeks and greater than 2x improvement over baseline at 12 weeks regardless of dose.

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MARKET OPPORTUNITIES

Immune Health

Spectramune offers full spectrum immune support deployable in innovative consumer immune health products.

Cognitive/Mood

People using Spectramune reported feeling better and healthier in a Perceived Immune Function test.

Healthy Aging

Aging human immune systems become less effective at tackling infections. Spectramune can support aging immune systems.

ORIGIN STORY

Ashwagandha and Haritaki

The research examined botanical extract synergies and evaluated which combination of these showed the best potential. At the end of the process, it was a 1:1 ratio of ashwagandha (Withania somnifera) and Haritaki (Terminalia chebula).

An intensive search of traditional botanical medicine

The development of Spectramune Immune Defense Complex started with a few simple questions: “how can we create something new in the immune health space that is based on botanicals rather than traditional polysaccharides or other fibers from fungal sources?

Support Immune Function

Researchers at PLT innovation partner Laila Nutraceutical began a screening process that examined forty different botanicals known from scientific literature or traditional medicine to have the ability to support immune function.

Evaluation of Plant Extracts

The plant extracts were evaluated for:

IL-2 production
IFN gamma production
Lymphocyte proliferation in primary human peripheral blood cells

The list of plants was narrowed down to the four with the best activity in all three assays.

Ashwagandha and Haritaki

An intensive search of traditional botanical medicine

Support Immune Function

Evaluation of Plant Extracts

The plant extracts were evaluated for:

IL-2 production
IFN gamma production
Lymphocyte proliferation in primary human peripheral blood cells

The list of plants was narrowed down to the four with the best activity in all three assays.

Ashwagandha and Haritaki

Clinically Backed, Full-Spectrum Support

Immune support is top of mind for consumers in all walks of life. But many of the ingredient solutions on the market have failed to address emerging pain points in the immune supplement space. Spectramune® Immune Defense Complex is a proprietary, botanical ingredient complex that brings something new and exciting to the immune health space. The unique Spectramune combination was shown to support immune function in an experimental immunosuppression model. Impressive results and an excellent safety profile prompted the ingredient to be taken into randomized controlled trials in humans, where its efficacy was further validated.

Formulators of immune health products can use Spectramune as a foundational ingredient or in combination with existing formulas to address a wide range of a consumer’s immune health needs.

Spectramune® Product Sheet

May 1, 2024

Behind every ingredient solution is an even better story, download the product sheet to learn more.

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A randomized, double-blind, placebo-controlled clinical study to evaluate the effect of LN20189 (Spectramune) on immune function in healthy subjects

Clinical Research

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A randomized, double-blind, clinical study to evaluate the effect of Spectramune in mild to moderate COVID-19 subjects

Clinical Research

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PLT Introduces Novel, Patented, Broad Spectrum Immune Health Ingredient

April 24, 2023

PLT Health Solutions, Inc is launching a novel ingredient to support immune health. Called Spectramune® Immune Defense Complex, the ingredient is a patented, synergistic combination of ashwagandha (Withania somnifera) and Haritaki (Terminalia chebula).

Press Releases

PLT Health Solutions Announces New Clinical Study on Spectramune® Immune Defense Complex that Demonstrates Reduced Incidence of Illness and Less Severe Symptoms

February 18, 2025

Third Clinical Study Confirms Spectramune’s Comprehensive Immune Health Benefits

Press Releases

Clinical Study on Spectramune® Immune Defense Complex that Demonstrates Reduced Incidence of Illness and Less Severe Symptoms

Clinical Research

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Spectramune® Immune Defense Complex

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