Supresa® Crave Control

Give them More Power Against Snacking

69% Decreased Hunger

Studies show that Supresa can help dieters be less hungry compared to baseline.

55% Reduced Snacking

Users of Supresa showed a reduction in snacking incidents compared to baseline.

Infinite

Supresa is an ingredient that can complement any weight management product or program.

14
Days

Clinical studies show that Supresa starts giving people the power to control cravings starting within 2 weeks.

	Clinically studied
	Fast-acting
	Complementary mechanism of action
	Safe, side-effect free
	Exciting consumer messaging
	Sustainable
	Vegan suitable
	Water-soluble

CERTIFICATIONS

GLUTEN-FREE

NON-GMO

HALAL

KOSHER

GRAS

A Novel Extract of Saffron

Supresa is an extract of Crocus sativus L. saffron stigmas, is rich in safranal, crocin and picrocin. This proprietary extract is standardized to >0.3% safranal. Supresa was developed to support weight management, by improving emotional wellbeing and decreasing snacking behavior. Unlike other products, Supresa does not act acutely to promote a feeling of ‘fullness.’ Rather, it induces a feeling of wellbeing and stress reduction over time to address the source of stress-related overeating and snacking.

Flowering Plant
in The Iris Family

Crocus sativus, commonly known as saffron crocus or autumn crocus, is a species of flowering plant in the iris family.

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The Magic of Saffron

Saffron is cultivated and is best known for the culinary use of its floral stigmas as the spice saffron.

Rhodiola rosea

Rhodiola rosea is a plant native to remote Arctic climates in Asia, Europe and North America.

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Exciting Phytochemistry

The root of the plant contains around 140 chemical compounds including phenols, rosavin, rosarin, salidroside and more.

Detail 1

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

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Detail 2

Kale chips cold-pressed put a bird on it mumblecore kogi brooklyn farm-to-table blue bottle yuccie authentic kombucha migas. Literally tilde tacos paleo.

Research that Builds Trust with Consumers

No matter what your program is, why not add Supresa to your product and give your customers the state-of-mind they’ll need to help them succeed. Supresa induces a feeling of well-being and stress reduction to address the source of stress-related overeating and snacking – a different mechanism of action for weight management from other weight management ingredients.

In a study conducted with 60 healthy, only slightly overweight women (BMI 25-30) who were between 25-45 years old, Supresa intake over t8 weeks resulted in significantly greater body weight reduction than the placebo group. Supresa decreased snacking by 55% compared to a 28% reduction by the placebo group. The decrease in appetite was 69% in the Supresa group versus 54% in the placebo group. There were no reports of side effects in the study groups, and compliance with the Supresa regimen was excellent.

Supresa Aids in Weight Management

A double-blind placebo-controlled study shows that Supresa may decrease hunger, and reduce snacking between meals. Clinical studies have shown that women taking Supresa report decreased hunger. Weight loss has also been demonstrated.

Clinical Study: Supresa Supports Weight Loss and Less Snacking

Supresa Supports Weight Loss and Less Snacking_chart

Supresa intake over 8 weeks resulted in significantly greater body weight reduction, decreased snacking by 55% and a decrease in appetite of 69%.

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ACCESS CLINICAL STUDIES

MARKET OPPORTUNITIES

Weight Management

Supresa can be used in a range of ‘fun’ foods and beverages including lollipops, gums, chews and shakes to help curb snacking.

Active/Sports Nutrition

For bodybuilders and physique trainers, Supresa can help regulate when and where they’ll eat before competition.

APPLICATIONS

CHEWS

CONFECTIONARY

EFFERVESCENTS

GUMMIES

POWDERS

RTDS/SHOTS

SOFT GELS

STICK PACKS

TABLETS

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ORIGIN STORY

Helping Create Opportunity in Impoverished Areas

Crocus sativus L., known as saffron, is a plant whose dried stigmas are a popular spice and food condiment renowned for its color, aroma, and flavor. Supresa is made from selected partners involved with saffron harvest.

A Rich Traditional Heritage

Saffron is cultivated in India, Spain, Iran, Afghanistan, and Greece, with suppliers offering various grades of saffron. Saffron has a rich traditional heritage for its medicinal use in addition to worldwide usage as a coloring and flavoring agent.

Sustainable and Socially Responsible

In keeping with innovation partner NATAC’s philosophy, every aspect of Supresa’s production is continually evaluated with sustainability and social responsibility in mind. Water and energy use are minimized in the process.

High Value in Global Markets

Saffron farming, which is highly labor intensive, is a way that local communities can rise from poverty because of its high value in global markets. Economically, if each family had one jerib (half an acre) of land for saffron, they would rise from poverty.

Opportunities for Women

Cultivation and production of saffron creates numerous job opportunities, especially for women who perform 80 percent of this work. NATAC is committed to working with saffron farming operators who pay an equitable wage and provide good working conditions.

A Unique Mechanism of Action

Many ingredients designed to inhibit the desire to snack act on physiological or hormonal factors. Supresa’s clinically studied formula improves levels of the neurotransmitter serotonin. The proposed mechanism of action through which Supresa is thought to exert efficacy is by serotonin reuptake inhibition (Perovic, 1995 unpublished data), whereby a sense of wellbeing is achieved. Serotonin is a neurotransmitter that influences satiety, appetite, mood, compulsiveness and anxiety. It is notable that Supresa consistently shows greater than 50% inhibition of serotonin reuptake from lot-to-lot testing, whereas the same results were not obtained from generic saffron extracts (unpublished data on file).

Modes of Weight Loss

Obesity is a complex problem due to multiple mechanisms involved in energy metabolism.

• Highly conserved by redundant mechanisms

• Regulated by many pathways

• Effective weight management should target multiple mechanisms

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Incredible formulation versatility

If you are talking about a weight loss supplement, Supresa can be added as an ingredient to improve the performance of that supplement – adding the dimension of crave control – or what we are calling ‘power against snacking’ – to the formula. The same holds true for diets and meal plans.

Ideal applications for Supresa as an ingredient in the food space include gummies and chews, bars of all kinds including protein bars, a range of snacks and meal replacements. In the beverage space, Supresa has been explored in coffee and tea drinks, milk beverages, fruit beverages and shakes – as well as ‘shots’.

Adding Supresa will not change the taste or appearance of products. From a formulating standpoint can be mixed with vitamins, minerals, starches, flavors, aromas, sweeteners for easy incorporation.

Global Intellectual Property

Supresa is the only saffron-based weight loss ingredient with patent protection in global markets. The patents cover the use of saffron, the saffron extracts crocin and picrocrocin, and derivatives of these, as an ingredient in support of a healthy weight.

Global Patents Issued: US 9,833,489 B2 Canada: 2648985 Europe: 2,010,012 Japan: 6,093,425

Supresa™ Product Sheet

April 02, 2020

A clinically studied, fast-acting ingredient that can enhance any weight management product, program or diet.

Sales Collateral

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Supresa™ reduces snacking and increases satiety in a randomized placebo-controlled study

Clinical Research

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Our international network, passionate team of experts and extensive industry knowledge is what sets us apart.

Supresa® Crave Control

OVERVIEW

Gaining control of your snack craving should be a part of any weight management program.

69% Decreased Hunger

55% Reduced Snacking

Infinite

14Days

FEATURES & BENEFITS

Clinically studied

Fast-acting

Complementary mechanism of action

Safe, side-effect free

Exciting consumer messaging

Sustainable

Vegan suitable

Water-soluble