Evaluation of the anti-wrinkle effects of the food supplement Collactive®: A randomized, placebo-controlled study

Citation: [No authors listed] Evaluation of the anti-wrinkle effects of the food supplement Collactive^®: A randomized, placebo-controlled study. [Data on file]

Abstract: The aim of this study was to evaluate the anti-ageing effect of a commercial product based on collagen and elastin peptides: Collactive^®. A randomized, controlled, single-blind study was conducted on healthy female subjects. Forty-four subjects aged 40 to 55 years old and with wrinkles on the crow’s feet were included. Twenty-two subjects were supplied with the active product for 3 months and twenty-two with the placebo. Anti-wrinkle and moisturizing effects were assessed on crow’s feet by objective methods, following 28 days and 84 days of products consumption; tolerance and global appreciation were directly evaluated by subjects at the end of the study, using self questionnaires. After 3 months of supplementation, the number of deep wrinkles decreased in the active group and a significant difference was seen between the two groups on this parameter (p<0.05). No intergroup difference was highlighted on microrelief furrows and average wrinkles but a difference limit to significance was observed on the total wrinkled surface between the active and placebo groups (p<0.1). No adverse effect was reported during Collactive^® supplementation. This study demonstrates the skin anti-ageing benefits of Collactive^®: results suggest that Collactive^® prevents and diminishes wrinkles on crow’s feet.