Strengthera™ Muscle Maintenance+Vitality

Improvement in Grip Strength

Strengthera improved grip strength versus baseline and placebo at the earliest timepoint assessed: 4 weeks. By 12 weeks, subjects in the Strengthera group improved their grip strength 4.5x more than those doing the same exercises and taking placebo (1.9 kg  vs. 0.42 kg).

Improvement in Muscle Endurance

Assessed as 1RM repetitions to failure, Strengthera improved muscle endurance/active capacity versus baseline and placebo at the earliest timepoint assessed of 4 weeks. By 12 weeks, this represented a 50% improvement in active capacity over  subjects doing the same exercises and taking placebo.

Improvement in Walking Capacity

Walking Capacity, measured as distance or speed, was tested via a 6-minute walk test. Strengthera improved walking capacity versus baseline at 4 weeks. By 12 weeks, the improvement was statistically significant versus placebo. This represented a 1.9x improvement in walking capacity over the placebo. A 25.64 m distance improvement was observed for Strenthera subjects versus a 13.78 m improvement for the placebo group. A 4.27 m/min speed improvement was seen in Strengthera subjects versus a 2.3 m/min improvement in the placebo group.

Improvement in Lean Mass

The Strengthera group increased their total lean mass relative to baseline. While the actual values were not statistically significant between groups, the analysis of change scores showed statistically a significant difference versus placebo in the amount of lean mass gained over 12 weeks.

† Statistically significant difference vs. baseline values
^Statistically significant difference vs. placebo